1322805-10-6Relevant articles and documents
Chemoenzymatic dynamic kinetic resolution of primary amines catalyzed by CAL-B at 38-40°c
Poulhes, Florent,Vanthuyne, Nicolas,Bertrand, Michele P.,Gastaldi, Stephane,Gil, Gerard
experimental part, p. 7281 - 7286 (2011/10/10)
The (R)-selective chemoenzymatic dynamic kinetic resolution of primary amines was performed at 38-40 °C in MTBE, in good to high yields and with high enantiomeric excesses. These reactions associating CAL-B to octanethiol as radical racemizing agent were carried out in the presence of methyl β-methoxy propanoate as acyl donor, under photochemical irradiation at 350 nm in glassware.