132286-86-3

Upstream product

• 133464-16-1 (R)-2-tert-Butoxycarbonylamino-5-chloro-4-oxo-pentanoic acid benzyl ester 
• 17356-08-0 thiourea 
• 92828-64-3 (R)-2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester 

Downstream Products

• 150114-17-3 (R)-3-(2-Benzyloxycarbonylamino-thiazol-4-yl)-2-tert-butoxycarbonylamino-propionic acid benzyl ester 
• 135703-71-8 {4-[(R)-2-tert-Butoxycarbonylamino-2-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-ethyl]-thiazol-2-yl}-carbamic acid benzyl ester 
• 135703-72-9 {4-[(R)-2-Amino-2-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-ethyl]-thiazol-2-yl}-carbamic acid benzyl ester 
• 135704-23-3 (R)-3-(2-Benzyloxycarbonylamino-thiazol-4-yl)-2-tert-butoxycarbonylamino-propionic acid 
• 135727-10-5 (4-{(R)-2-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-[(S)-2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-ethyl}-thiazol-2-yl)-carbamic acid benzyl ester 
• 135760-05-3 <1S-(1R*,2S*,3R*)>-N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-<2,3-dihydroxy-5-methyl-1-(cyclohexylmethyl)hexyl>-D-alaninamide 

Relevant academic research and scientific papers

Synthesis of Enantiomerically Pure Amino Acids Containing a 2-Amino-4-thiazolyl Side Chain

Enantiomerically pure 2-amino-4-thiazolyl containing amino acids were readily synthesized from commercially available derivatives of aspartic acid and glutamic acid, via reaction with diazomethane and further cyclization with thiourea.