135760-05-3

Upstream product

• 135727-10-5 (4-{(R)-2-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-[(S)-2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-ethyl}-thiazol-2-yl)-carbamic acid benzyl ester 
• 122621-77-6 (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane 
• 132286-86-3 (R)-3-(2-Amino-thiazol-4-yl)-2-tert-butoxycarbonylamino-propionic acid benzyl ester 
• 135704-23-3 (R)-3-(2-Benzyloxycarbonylamino-thiazol-4-yl)-2-tert-butoxycarbonylamino-propionic acid 
• 135703-72-9 {4-[(R)-2-Amino-2-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-ethyl]-thiazol-2-yl}-carbamic acid benzyl ester 
• 150114-17-3 (R)-3-(2-Benzyloxycarbonylamino-thiazol-4-yl)-2-tert-butoxycarbonylamino-propionic acid benzyl ester 
• 135703-71-8 {4-[(R)-2-tert-Butoxycarbonylamino-2-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-ethyl]-thiazol-2-yl}-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Structure-Activity Relationships of a Series of 2-Amino-4-thiazole-Containing Renin Inhibitors

A series of renin inhibitors was synthesized that contained a 2-amino-4-thiazolyl moiety at the P2 position.These derivatives are potent inhibitors of monkey renin in vitro and are selective in that they only weakly inhibit the closely related