132289-59-9Relevant academic research and scientific papers
A New Mode of Reactivity of N-Methoxy-N-methylamides with Strongly Basic Reagents
Graham, Samuel L.,Scholz, Thomas H.
, p. 6269 - 6272 (1990)
In applying N-methoxy-N-methylamides as acylating agents for carbanions, an unusual mode of reactivity was discovered.In particular, competitive transfer of a hydroxymethyl group was observed.The mechanism of this reaction is described, and involves a base induced E2 elimination of the N-methoxy-N-methylamide generating formaldehyde and the corresponding N-methylamide anion.
