Tetrahedron Letters p. 6269 - 6272 (1990)
Update date:2022-08-04
Topics:
Graham, Samuel L.
Scholz, Thomas H.
In applying N-methoxy-N-methylamides as acylating agents for carbanions, an unusual mode of reactivity was discovered.In particular, competitive transfer of a hydroxymethyl group was observed.The mechanism of this reaction is described, and involves a base induced E2 elimination of the N-methoxy-N-methylamide generating formaldehyde and the corresponding N-methylamide anion.
View MoreJiangsu Chiatai Qingjiang Pharmaceutical Co.,Ltd
Contact:+86-517-86283327
Address:9 North Hantai Road, Huaian, China
Taizhou Crene Biotechnology co.ltd
Contact:86-576-88813233 88205808
Address:Economic Developed Zone of Taizhou Zhejiang China
lianyungang jinkang pharmaceutical technology co., ltd.
Contact:008651885445517
Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
website:http://www.konochem.com
Contact:86-29-86107037
Address:No.170 West Avenue,Xi’an 710082,China
Contact:86-571-86737118-8689
Address:No.69, 12 Street, HEDA, Hangzhou, Zhejiang, China
Doi:10.1016/S0040-4039(00)97252-6
(1990)Doi:10.1039/c1cc12757h
(2011)Doi:10.1016/S0040-4039(00)99166-4
(1989)Doi:10.1002/anie.201102102
(2011)Doi:10.1515/znb-2011-0605
(2011)Doi:10.1039/c5cc02127h
(2015)
