13229-87-3Relevant academic research and scientific papers
Novel N-chlorinated derivatives of 2H-1-benzopyran-2-imines
Volmajer, Julija,Toplak, Renata,Bittner, Shmuel,Leban, Ivan,Le Marechal, Alenka Majcen
, p. 2363 - 2366 (2003)
A series of new N-chlorobenzopyran-2-imines were prepared in moderate to good yields, by reacting sodium hypochlorite in an acidic medium with benzopyran-2-imines obtained via the Knoevenagel condensation. Some of the N-chlorobenzopyran-2-imines obtained are potential antiproliferating agents.
Synthesis of new iminocoumarins and their transformations into N-chloro and hydrazono compounds
Volmajer, Julija,Toplak, Renata,Leban, Ivan,Le Marechal, Alenka Majcen
, p. 7012 - 7021 (2005)
The Knoevenagel reaction between 2-hydroxybenzaldehydes and active methylene compounds (malononitrile and ethyl cyanoacetate) produces iminocoumarins and/or coumarins. In order to study the reactivity of the prepared iminocoumarins, chlorination and reaction with N-nucleophiles were studied.
