13230-06-3

Basic information

• Product Name: 1H-Imidazole, 2-methyl-4-nitro-1-(phenylmethyl)-
• CAS NO: 13230-06-3
• Molecular Formula: C11H11N3O2
• Molecular Weight: 217.227
• Mol File: 13230-06-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 2-methyl-4-nitro-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 2-methyl-4-nitro-1-(phenylmethyl)-(13230-06-3)
• EPA Substance Registry System: 1H-Imidazole, 2-methyl-4-nitro-1-(phenylmethyl)-(13230-06-3)

Safety Data

• Hazardous Substances Data: 13230-06-3(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 696-23-1 2-methyl-4-nitro-1H-imidazole 
• 13230-44-9 1-benzyl-2-methyl-5-nitro-1H-imidazole 
• 696-23-1 2-methyl-5-nitro-1H-imidazole 
• 100-39-0 benzyl bromide 

Downstream Products

• 256530-58-2 1-Benzyl-5-dichlormethyl-2-methyl-4-nitroimidazol 
• 107108-05-4 5-(Cyano-4-morpholinylphenylmethyl)-2-methyl-4-nitro-1-(phenylmethyl)-1H-imidazole 
• 107108-07-6 (2-Methyl-4-nitro-1-(phenylmethyl)-1H-imidazol-5-yl)phenylmethanone 
• 256530-69-5 4-(1-Benzyl-2-methyl-4-nitro-imidazol-5-yl)-2,6-dimethyl-pyridin-3,5-dicarbonsaeuredimethylester 
• 256530-63-9 4-(1-Benzyl-2-methyl-4-nitro-imidazol-5-yl)-1,4-dihydro-2,6-dimethyl-pyridin-3,5-dicarbonsaeuredimethylester 
• 256530-60-6 1-Benzyl-2-methyl-4-nitroimidazol-5-carbaldehyd 
• 41604-61-9 5-Bromo-2-methyl-4-nitro-1-(phenylmethyl)-1H-imidazole 

Relevant articles and documents

Solid-liquid phase-transfer catalytic method for N-alkylation of nitroimidazole

A variety of 1-alkyl-2-methyl-4-nitroimidazoles have been synthesized with a solid-liquid phase-transfer catalytic method in excellent yields.

Regioselective Alkylation of 4(5)-Nitro-1H-Imidazoles in Acidic Media: Study of Temperature Effects

Alkylation of 4(5)-nitro-1H-imidazoles in acidic media with reactive alkylating agents such as benzyl chloride and allyl bromide resulted in the predominant formation of the 5-nitro isomers at lower temperatures (75 deg C) and the 4-nitro isomers at higher temperatures (140 deg C).With less reactive alkylating agents, only the 5-nitro isomers were produced irrespective of temperature.The mechanism was shown to involve quaternization of the initially formed 1-alkyl-5-nitro-1H-imidazoles followed by preferential dealkylation to yield the thermodynamically more stable 4-nitro-1H-imidazoles.