132305-91-0Relevant academic research and scientific papers
Synthesis and antibacterial activity of thiazolopyrazine-incorporated tetracyclic quinolone antibacterials
Inoue,Kondo,Taguchi,Jinbo,Sakamoto,Tsukamoto
, p. 586 - 592 (2007/10/02)
A novel series of 8-substituted-9,1-[(N-methylimino)methano]-7-fluoro-5- oxo-5H-thiazolo[3,2-α]-quinoline-4-carboxylic acids 5a-q having a unique thiazolopyrazine-incorporated tetracyclic structure were synthesized, and the in vitro and in vivo activities
Quinolinecarboxylic acid derivatives, antibacterial agent containing the same
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, (2008/06/13)
Novel quinolinecarboxylic acid derivatives of the formula: STR1 wherein Z is STR2 or STR3 in which R1 is hydrogen atom, a halogen atom, hydroxy or a lower alkyloxy; R2 is a halogen atom, hydroxy or a lower alkyloxy; R3 is a lower alkyl; and R4 is hydroxy or a di(lower alkyl)amino, and a pharmaceutically acceptable salt thereof, which have excellent antibacterial activities and are useful as an antibacterial agent, a pharmaceutical composition containing the same, and process for preparing the same.
