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Product FOB Price Min.Order Supply Ability Supplier
1,3-Dichloroacetone
Cas No: 534-07-6
USD $ 500.0-500.0 / Gram 1 Gram 1000 Gram/Day Pure Chemistry Scientific Inc. Contact Supplier

534-07-6 Usage

Applications

1,3-Dichloroacetone is employed in the synthesis of citric acid. Additionally, it is used as an intermediate and a solvent in organic synthesis. Furthermore, 1,3-Dichloroacetone is utilized as an acceptor substrate in the cross-aldol reaction with donor substrates such as clyclohexanone, cyclopentanone, and acetone. 1,3-Dichloroacetone is also employed in the preparation of famotidine which is an active pharmaceutical ingredient.

Fire Hazard

When heated to decomposition, 1,3-Dichloroacetone emits highly toxic fumes of chlorides. 1,3-Dichloroacetone may burn but does not ignite readily. Container may explode in heat of fire.

Description

1,3-Dichloroacetone is a chemical substance with the molecular formula C3H4Cl2O. TLC has discovered that it is a metabolite of 1,3-dichloropropanol. The crystalline solid is denser than water and is not water-soluble.

Air & Water Reactions

Insoluble in water.

Chemical Properties

White or colorless crystals

General Description

A crystalline solid. Denser than water and insoluble in water. Inhalation of dust or powder may cause adverse health reactions.

Safety

When exposed or inhaled, 1,3-Dichloroacetone can result in damage or irritation to eyes, lungs, throat, kidney, and kidneys. It can also lead to fainting and headaches. The substance has been classified as extremely hazardous in America.

Health Hazard

1,3-Dichloroacetone may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution.

Reactivity Profile

A halogenated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Purification Methods

Crystallise it from CCl4, CHCl3 or *benzene and/or distil under vacuum [Conant & Quayle Org Synth Coll Vol I 211 1941, Hall & Sirel J Am Chem Soc 74 836 1952]. It is dimorphic [Daasch & Kagarise J Am Chem Soc 77 6156 1955]. The oxime has m 130-131o, b 106o/25mm [Arzneimittel-Forsch 8 638 1958]. [Beilstein 1 IV 3219.]

534-07-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3-Dichloroacetone

1.2 Other means of identification

Product number -
Other names 2-Propanone, 1,3-dichloro-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:534-07-6 SDS

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