132308-86-2Relevant academic research and scientific papers
Solid phase synthesis of benzimidazole ketones and benzimidazole chalcones under solvent-free conditions
Dubey,Kumar, C. Ravi,Babu, Balaji
, p. 3128 - 3130 (2007/10/03)
Oxidation of 1-alkyl/aralkyl-2-(α-hydroxyalkyl/aryl)benzimidazoles 1 with KMnO4 on neutral alumina under solid phase conditions gives the corresponding ketones, 1-alkyl/aralkyl-2-acyl-benzimidazoles 2. Compound 2a (R2 = CH3) on condensation with aromatic aldehydes in the presence of solid NaOH under solvent-free conditions, yields the corresponding chalcones, 1-alkyl/aralkyl-2-benzimidazole aryl vinyl ketone 3.
