1323264-48-7

Upstream product

• 1779-49-3 Methyltriphenylphosphonium bromide 
• 267666-09-1 1-((2-nitrophenyl)sulfonyl)piperidin-4-one 

Downstream Products

• 1323264-34-1 dimethyl 4-{[1-(2-nitrobenzenesulfonyl)piperidin-4-yl]methyl}pyridine-2,6-dicarboxylate 
• 1323264-42-1 4-tert-butoxycarbonylamino-1-[6-tert-butoxycarbonylamino-4-([{[1-(2-nitrobenzenesulfonyl)piperidin-4-yl]methyl}pyridin-2-yl]methyl)]piperidine 
• 1323264-39-6 [6-tert-butoxycarbonylamino-4-{[1-(2-nitrobenzenesulfonyl)piperidin-4-yl]methyl}pyridine-2-yl]methanol 
• 1323264-37-4 methyl 6-tert-butoxycarbonylamino-4-{[1-(2-nitrobenzenesulfonyl)piperidin-4-yl]methyl}pyridine-2-carboxylate 
• 1323264-35-2 6-methoxycarbonyl-4-{[1-(2-nitrobenzenesulfonyl)piperidin-4-yl]methyl}pyridine-2-carboxylic acid 
• 1323264-51-2 N-(1-[{6-amino-4-[(1-propylpiperidin-4-yl)methyl]pyridin-2-yl}methyl]piperidin-4-yl)-2-cyclopentyl-2-hydroxy-2-phenylacetamide 

Relevant academic research and scientific papers

Synthesis of 5-Acyl-4-methylene-1,2,3,4-Tetrahydropyridines

Several approaches to monocyclic N-protected 4-methylene-1,2,3,4-Tetrahydropyridines are reported. N-Boc-4-methylenepiperidin-3-one was found to be unstable and its enol triflate was not easily accessible. However, N-protected 2,3-dihydropyridin-4-ones ar

Synthesis of antagonists of muscarinic (M3) receptors

Several α-hydroxyamides with (2,6-dialkoxyphenoxy)methyl substituents have been prepared and their activities as antagonists of the M3 muscarinic receptor in guinea pig ileum have been evaluated. N-{1-[(Phenyl)methyl]piperidin-4-yl}-2-{2-[(2,6-dimethoxyphenoxy)-methyl]phenyl} -2-hydroxypropanamide and N-(1-[{6-amino-4-[(1-propylpiperidin-4-yl)methyl]- pyridin-2-yl}methyl]piperidin-4-yl)-2-cyclopentyl-2-hydroxy-2-phenylacetamide were the most potent compounds prepared, the micromolar potency of the latter indicating that it may be worth further investigation.