1323276-55-6

Basic information

• Product Name: (S)-N-(2-(3-(2-cyanophenoxy)-2-hydroxypropylamino)ethyl)-6-fluoronicotinamide
• Synonyms: (S)-N-(2-(3-(2-cyanophenoxy)-2-hydroxypropylamino)ethyl)-6-fluoronicotinamide
• CAS NO: 1323276-55-6
• Molecular Weight: 358.372
• Mol File: 1323276-55-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-N-(2-(3-(2-cyanophenoxy)-2-hydroxypropylamino)ethyl)-6-fluoronicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-(2-(3-(2-cyanophenoxy)-2-hydroxypropylamino)ethyl)-6-fluoronicotinamide(1323276-55-6)
• EPA Substance Registry System: (S)-N-(2-(3-(2-cyanophenoxy)-2-hydroxypropylamino)ethyl)-6-fluoronicotinamide(1323276-55-6)

Safety Data

• Hazardous Substances Data: 1323276-55-6(Hazardous Substances Data)

Upstream product

• 403-45-2 6-fluoronicotinic acid 
• 1355672-43-3 C₈H₁₀FN₃O 
• 93744-18-4 (S)-(+)-3-(2-cyanophenoxy)-1,2-epoxypropane 
• 1323277-15-1 C₁₃H₁₈FN₃O₃ 

Relevant articles and documents

Synthesis and cardiac imaging of 18F-ligands selective for β1-adrenoreceptors

A series of potent and selective β1-adrenoreceptor ligands were identified (IC50 range, 0.04-0.25 nM; β1/ β2 selectivity range, 65-450-fold), labeled with the PET radioisotope fluorine-18 and evaluated in normal Sprague-Dawley rats. Tissue distribution studies demonstrated uptake of each radiotracers from the blood pool into the myocardium (0.48-0.62% ID/g), lung (0.63-0.97% ID/g), and liver (1.03-1.14% ID/g). Dynamic μPET imaging confirmed the in vivo dissection studies.