132336-30-2 Usage
Uses
Used in Cardiovascular Applications:
2(1H)-Pyrimidinone, 4-amino-1-[(2S)-2-hydroxy-3-(triphenylmethoxy)propyl]is used as an antihypertensive agent for the treatment of high blood pressure. It operates by blocking the action of angiotensin II, a potent vasoconstrictor, which in turn leads to the relaxation of blood vessels and a decrease in blood pressure.
Used in Heart Failure Treatment:
In the context of heart failure, 2(1H)-Pyrimidinone, 4-amino-1-[(2S)-2-hydroxy-3-(triphenylmethoxy)propyl]is utilized to improve the symptoms and outcomes for patients. It aids in reducing the workload on the heart by dilating blood vessels, thus improving cardiac function and overall patient prognosis.
Used in Post-Heart Attack Recovery:
2(1H)-Pyrimidinone, 4-amino-1-[(2S)-2-hydroxy-3-(triphenylmethoxy)propyl]is employed to improve survival rates and recovery after a heart attack. By managing blood pressure and reducing the strain on the heart, it contributes to better outcomes for individuals who have experienced myocardial infarction.
Used in Diabetic Nephropathy Prevention:
For patients with diabetes, 2(1H)-Pyrimidinone, 4-amino-1-[(2S)-2-hydroxy-3-(triphenylmethoxy)propyl]is used to prevent kidney problems, a common complication of diabetes known as diabetic nephropathy. Its blood pressure-lowering effects help in preserving renal function and slowing the progression of kidney disease.
Used in Combination Therapy:
2(1H)-Pyrimidinone, 4-amino-1-[(2S)-2-hydroxy-3-(triphenylmethoxy)propyl]can be used in combination with other medications to achieve a synergistic effect in treating high blood pressure and heart-related conditions. This approach allows for more effective management of symptoms and improved patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 132336-30-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,3,3 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 132336-30:
(8*1)+(7*3)+(6*2)+(5*3)+(4*3)+(3*6)+(2*3)+(1*0)=92
92 % 10 = 2
So 132336-30-2 is a valid CAS Registry Number.
132336-30-2Relevant academic research and scientific papers
Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
-
Page/Page column 55, (2015/03/03)
The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of ph
Phosphonate Ester Derivatives and Methods of Synthesis Thereof
-
Page/Page column 19, (2012/03/26)
The disclosure describes methods of synthesis of phosphonate ester derivatives. Preferred methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity. In some embodiments, preferred methods accor
CIDOFOVIR PEPTIDE CONJUGATES AS PRODRUGS
-
Page/Page column 11; figure 3, (2008/06/13)
Cidofovir-based compounds having an amino acid, dipeptide or tripeptide attached to a cidofovir or cyclic cidofovir framework. The compounds show enhanced oral bioavailability and increased binding to the PepT1 transporter. The present invention also provides compositions and methods for treating virus infections, and a method of preparing cidofovir.
A Practical Synthesis of (S)-HPMPC
Brodfuehrer, Paul R.,Howell, Henry G.,Sapino, Chester Jr.,Vemishetti, Purushotham
, p. 3243 - 3246 (2007/10/02)
Synthesis of the title nucleotide was accomplished in high yield starting from (S)-tritylglycidol (5) and N-benzoylcytosine (9).
