132367-16-9Relevant academic research and scientific papers
Oxidative decarboxylation of naproxen
Bosca,Martinez-Manez,Miranda,Primo,Soto,Vano
, p. 479 - 482 (2007/10/02)
The decarboxylation of naproxen (1H) and its salt (1-) was achieved by means of chemical [Ce(IV) or S2O8/2-] and electrochemical oxidation. The product patterns were compatible with mechanisms involving single-electron transfer from the pl-system or the carboxylate moiety. The results are discussed in connection with the involvement of electron-transfer processes in the reported phototoxicity of naproxen.
