13237-44-0

Upstream product

• 1136-29-4 (4α,4aα,8aα)-decahydro-1,6-bis(methylene)-4-(1-methylethyl)naphthalene 
• 483-75-0 (-)-α-muurolene 
• 24268-39-1 γ-muurolene 
• 317819-78-6 1,3-dimethyl-8-propan-2-yltricyclo[4.4.0.02,7]dec-3-ene 
• 7647-01-0 hydrogenchloride 
• 60-29-7 diethyl ether 
• 917-54-4 methyllithium 
• 1080-68-8 3,4,4aβ,7,8,8aα-hexahydro-4β-isopropylnaphthalene-1,6(2H,5H)-dione 
• 5957-56-2 (+/-)-γ₂-cadinene 
• 483-81-8 (8R,8aR)-8-Isopropyl-2,5-dimethyl-1,2,3,4,6,7,8,8a-octahydro-naphthalen-2-ol 
• 27548-51-2 (1R*,5S*,6S*)-(+/-)-5-Isopropyl-2-methylenbicyclo<4.4.0>decan-8-on 
• 81373-89-9 2-hydroxymethyl-8-isopropyl-5-methylene-Δ²-decalene 
• 81373-88-8 2-epoxy-8-isopropyl-5-methylenedecalin 
• 81373-90-2 8-isopropyl-2-mesyloxymethyl-5-methylene-Δ²-decalene 

Downstream Products

• 1136-29-4 (4α,4aα,8aα)-decahydro-1,6-bis(methylene)-4-(1-methylethyl)naphthalene 
• 1080-67-7 (+)-ε-Cadinen 
• 483-73-8 cis-cadinane 

Relevant academic research and scientific papers

A New Synthesis of (+/-)-γ2-Cadinene

8-Isopropyl-5-methylene-2-oxo-decalin (II) on nucleophilic epoxidation with dimethyloxosulphonium methylide under nitrogen atmosphere gives the epoxide (III) which undergoes stereoselective cleavage with lithium diisopropylamide to furnish the allylic alcohol, 2-hydroxymethyl-8-isopropyl-5-methyl-Δ2-decalene (IV).Conversion of IV into the corresponding mesylate (V) using mesyl chloride/TEA in dry dichloromethane and subsequent reduction of V with LAH yields (+/-)-γ2-cadinene (I).