132377-50-5

Basic information

• Product Name: syn-1-(p-methoxyphenyl)-3-methyl-4-p-tolylazetidin-2-one
• CAS NO: 132377-50-5
• Molecular Weight: 281.354
• Mol File: 132377-50-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: syn-1-(p-methoxyphenyl)-3-methyl-4-p-tolylazetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: syn-1-(p-methoxyphenyl)-3-methyl-4-p-tolylazetidin-2-one(132377-50-5)
• EPA Substance Registry System: syn-1-(p-methoxyphenyl)-3-methyl-4-p-tolylazetidin-2-one(132377-50-5)

Safety Data

• Hazardous Substances Data: 132377-50-5(Hazardous Substances Data)

Upstream product

• 161485-63-8 (E)-N-(4-methoxyphenyl)-1-(p-tolyl)methanimine 
• 292638-85-8 acrylic acid methyl ester 
• 132377-43-6 (2R,3R)-3-(4-Methoxy-phenylamino)-2-methyl-3-p-tolyl-propionic acid 
• 598-22-1 propanoyl bromide 
• 30669-07-9 4-methoxy-N-[(4-methylphenyl)methylidene]aniline 
• 132377-43-6 (2S,3R)-3-(4-Methoxy-phenylamino)-2-methyl-3-p-tolyl-propionic acid 

Relevant articles and documents

Diastereoselective Synthesis of syn-β-Lactams Using Rh-Catalyzed Reductive Mannich-Type Reaction of α,β-Unsaturated Esters

The combination of Et2Zn and RhCl(PPh3)3 led to the facile generation of a rhodium-hydride complex (Rh-H) that catalyzed the 1,4-reduction of α,β-unsaturated esters. The resulting rhodium enolate performed as a Reformatsky-type reagent and reacted with various imines to give syn-β-lactams in good to excellent yields with high diastereoselectivity.

A Convenient Method for β-Lactam Formation from β-Amino Acids Using Phenyl Phosphorodichloridate Reagent

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