1323976-01-7Relevant academic research and scientific papers
Synthesis of polysubstituted pyrroles via [3 + 2]-annulation of aziridines and -nitroalkenes under aerobic conditions
Wang, Shaoyin,Zhu, Xiancui,Chai, Zhuo,Wang, Shaowu
, p. 1351 - 1356 (2014/03/21)
Polysubstituted pyrroles were regioselectively synthesized in moderate to good yields via the copper acetate-catalyzed [3 + 2] annulation reaction of readily accessible aziridines and nitroalkenes. This reaction was proposed to proceed through a key azomethine ylide intermediate generated by selective C-C bond cleavage of the aziridine followed by annulation with nitroalkenes under aerobic conditions.
Three-component synthesis of polysubstituted pyrroles from α-diazoketones, nitroalkenes, and amines
Hong, Deng,Zhu, Yuanxun,Li, Yao,Lin, Xufeng,Lu, Ping,Wang, Yanguang
supporting information; experimental part, p. 4668 - 4671 (2011/10/30)
Polysubstituted pyrroles are regiospecifically synthesized via the copper-catalyzed three-component reaction of α-diazoketones, nitroalkenes, and amines under aerobic conditions. The cascade process involves an N-H insertion of carbene, a copper-catalyzed
