6832-17-3

Basic information

• Product Name: Ethanone, 2-diazo-1-(4-methoxyphenyl)-
• CAS NO: 6832-17-3
• Molecular Formula: C9H8N2O2
• Molecular Weight: 176.175
• Mol File: 6832-17-3.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-diazo-1-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-diazo-1-(4-methoxyphenyl)-(6832-17-3)
• EPA Substance Registry System: Ethanone, 2-diazo-1-(4-methoxyphenyl)-(6832-17-3)

Safety Data

• Hazardous Substances Data: 6832-17-3(Hazardous Substances Data)

Upstream product

• 31706-15-7 3-(4-methoxy-phenyl)-3-oxo-propionaldehyde 
• 15191-68-1 4,4,4-trifluoro-1-(4-methoxyphenyl)-1,3-butanedione 
• 186581-53-3 diazomethane 
• 6595-28-4 2-azido-1-(4-methoxyphenyl)ethan-1-one 
• 6327-79-3 1-(4-methoxyphenyl)-3-phenylpropane-1,3-dione 
• 18362-51-1 1,3-bis(4'-methoxyphenyl)propane-1,3-dione 
• 16208-17-6 2,2-dihydroxy-1-(4-methoxyphenyl)ethan-1-one 
• 1078202-81-9 C₁₂H₁₆N₂O₂Si 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 100-09-4 4-methoxybenzoic acid 
• 38502-65-7 1-(4-nitrophenyl)-3-(4-methoxyphenyl)propane-1,3-dione 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 72818-30-5 Anisoyl-4-tolylsulfon 
• 34933-41-0 sodium salt of p-methoxybenzoylacetaldehyde 

Downstream Products

• 21160-26-9 2-methoxy-1-(4-methoxy-phenyl)-ethanone 
• 86601-72-1 2-benzylamino-1-(4-methoxy-phenyl)-ethanol 
• 69163-82-2 5-(4-methoxyphenyl)-2-methyl-1,3-oxazole 
• 31191-57-8 1-(4-methoxy-phenyl)-2-(2-o-tolyl-benzo[d][1,3]thiazin-4-ylidene)-ethanone 
• 31191-58-9 1-(4-methoxy-phenyl)-2-[2-(4-methoxy-phenyl)-benzo[d][1,3]thiazin-4-ylidene]-ethanone 
• 35877-44-2 2-methylthio-5-(p-methoxyphenyl)oxazole 
• 77901-29-2 1-(4-Methoxy-phenyl)-2-(2,4,6-trimethoxy-phenyl)-ethanone 
• 3988-51-0 (E)-2-(3,4-dimethoxystyryl)-5-(4-methoxyphenyl)oxazole 
• 96845-67-9 2-Diazo-1-(4-methoxy-phenyl)-2-triethylsilanyl-ethanone 
• 96845-68-0 2-Diazo-1-(4-methoxy-phenyl)-2-triisopropylsilanyl-ethanone 
• 4136-21-4 p-methoxybenzoylmethanol 
• 62921-42-0 5-(4-methoxyphenyl)-2-phenyl-1,3-oxazole 

Relevant articles and documents

NovelN-transfer reagent for converting α-amino acid derivatives to α-diazo compounds

A novel universalN-transfer reagent for direct and effective transformation of α-amino ketones, acetamides, and esters to the corresponding α-diazo products under mild basic conditions has been developed. This one-step synthetic approach not only allows for generation of α-substituted-α-diazo carbonyl compounds from α-amino acid derivatives but also permits preparation of α-diazo dipeptides fromN-terminal dipeptides (32 examples, up to 91%).

Practical Application of the Aqueous 'Sulfonyl-Azide-Free' (SAFE) Diazo Transfer Protocol to Less α-C-H Acidic Ketones and Esters

The earlier described 'sulfonyl-Azide-free' ('SAFE') protocol for diazo transfer to CH-Acidic 1,3-dicarbonyl compounds (and their similarly activated congeners) has been extended to the less reactive monocarbonyl substrates, which previously required a se

Metal-Free Insertion Reactions of Diazo Carbonyls to Azlactones

Insertion reactions of diazo carbonyls to azlactones in basic conditions have been performed. The developed method allows the preparation of a wide range of oxazole derivatives in yields ranging from 74 to 98%. Different substituents on both azlactone rings and diazo carbonyls do not compromise the methodology, even those containing stereogenic centers. Isotopic labeling experiments revealed the mechanism may proceed through a rare diazo carbonyl activation by an ammonium salt derivative.