1323979-81-2Relevant academic research and scientific papers
Towards a catalytic asymmetric version of the [3+2] cycloaddition between hydrazones and cyclopentadiene
Zamfir, Alexandru,Tsogoeva, Svetlana B.
, p. 1988 - 1992 (2011)
A novel and easily accessible metal-free catalytic system, an in situ generated BINOL-phosphate-derived silicon Lewis acid, has been described for the [3+2] cycloaddition of N-benzoylhydrazone to cyclopentadiene to afford a cycloadduct in high diastereomeric ratio of 95:5 (syn/anti) and enantiomeric excess of 89%. These results provide insights in the future design and development of highly active and enantioselective silicon Lewis acids for this and other cycloaddition types. Georg Thieme Verlag Stuttgart - New York.
