13243-99-7

Basic information

• Product Name: 3'-Carboxy-4'-hydroxy-acetoacetanilide
• Synonyms: 3'-Carboxy-4'-hydroxy-acetoacetanilide
• CAS NO: 13243-99-7
• Molecular Formula: C11H11NO5
• Molecular Weight: 237.21
• Mol File: 13243-99-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 529.7 °C at 760 mmHg
• Flash Point: 274.1 °C
• Appearance: /
• Density: 1.449 g/cm³
• PKA: 2.97±0.10(Predicted)
• CAS DataBase Reference: 3'-Carboxy-4'-hydroxy-acetoacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-Carboxy-4'-hydroxy-acetoacetanilide(13243-99-7)
• EPA Substance Registry System: 3'-Carboxy-4'-hydroxy-acetoacetanilide(13243-99-7)

Safety Data

• Hazardous Substances Data: 13243-99-7(Hazardous Substances Data)

Usage

General Description

3'-Carboxy-4'-hydroxy-acetoacetanilide is a chemical compound with a molecular formula of C12H11NO5. It is a derivative of acetoacetanilide, a compound commonly used in the synthesis of various pharmaceuticals and dyes. The presence of a carboxy and hydroxyl group in this compound makes it useful in the development of drugs with analgesic and anti-inflammatory properties. Additionally, the chemical structure of 3'-Carboxy-4'-hydroxy-acetoacetanilide suggests that it may have potential as a chelating agent in metal ion extraction processes, as well as in the production of colorants and pigments. Overall, this compound has potential applications in the pharmaceutical and chemical industries due to its unique molecular structure and functional groups.

Upstream product

• 674-82-8 4-methyleneoxetan-2-one 
• 89-57-6 5-Aminosalicylic Acid 

Relevant articles and documents

Preparation method of 3-carboxyl-4-hydroxy-acetoacetanilide

The invention discloses a preparation method of 3-carboxyl-4-hydroxy-acetoacetanilide. The preparation method comprises the following steps: pumping a prescribed amount of soft water into a reaction kettle, adding caustic soda flakes to the reaction kettle, slowly adding 5-aminosalicylic acid to a sodium hydroxide solution, and adjusting and determining the pH value of the above obtained mixed solution to be about 7; and adjusting the temperature in the reaction kettle to be 18-27DEG C, slowly adding diketene in a dropwise manner, carrying out heat insulation by using the natural temperature, discharging the obtained material to a neutralization and crystallization kettle, filtering, carrying out centrifuge dewatering, and drying to obtain a finished product. The method has the advantages of simple operating steps, good working environment, mild reaction conditions, no special requirements on a device, realization of good quality and high yield of the product, and low energy consumption, and the 3-carboxyl-4-hydroxy-acetoacetanilide prepared through the method is not likely to agglomerate.