132454-41-2

Usage

Main properties

1. Chemical compound
2. Complex structure
3. Pyrrolidinedione ring
4. Benzoyl group
5. Chlorine atom
6. Methoxy groups
7. Used in chemical reactions
8. Used in organic synthesis
9. Reactive compound
10. Handle with caution

Specific content

Contains a pyrrolidinedione ring
Contains a benzoyl group attached to the ring
Contains a chlorine atom attached to the benzoyl group
Contains several methoxy groups attached to a phenyl ring
Used in various chemical reactions
Used in organic synthesis processes
Requires caution and adherence to safety protocols due to potential hazards.

Upstream product

• 132454-40-1 N-succinimidyl-4--hydroxymethyl-benzoate 
• 75-36-5 acetyl chloride 
• 132454-38-7 2-<4-(Bis-4-(methoxyphenyl)-hydroxymethyl)-phenyl>-4,4-dimethyl-1,3-oxazoline 
• 132454-39-8 4-Carboxy-4',4''-dimethoxyphenylhydroxymethane 
• 90-96-0 bis(p-methoxyphenyl)methanone 
• 32664-14-5 2-(4-bromophenyl)-4,4-dimethyl-2-oxazoline 

Downstream Products

• 132454-45-6 4-[[(2R,3S,5R)-3-Hydroxy-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-2-ylmethoxy]-bis-(4-methoxy-phenyl)-methyl]-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 132454-44-5 4-[[(2R,3S,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy]-bis-(4-methoxy-phenyl)-methyl]-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 132454-43-4 4-[[(2R,3S,5R)-5-(6-Benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy]-bis-(4-methoxy-phenyl)-methyl]-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 132454-49-0 4-[[(2R,3S,5R)-3-[(2-Cyano-ethoxy)-diisopropylamino-phosphanyloxy]-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-2-ylmethoxy]-bis-(4-methoxy-phenyl)-methyl]-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 132454-47-8 4-[{(2R,3S,5R)-5-(6-Benzoylamino-purin-9-yl)-3-[(2-cyano-ethoxy)-diisopropylamino-phosphanyloxy]-tetrahydro-furan-2-ylmethoxy}-bis-(4-methoxy-phenyl)-methyl]-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 132454-48-9 4-[{(2R,3S,5R)-5-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3-[(2-cyano-ethoxy)-diisopropylamino-phosphanyloxy]-tetrahydro-furan-2-ylmethoxy}-bis-(4-methoxy-phenyl)-methyl]-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 132454-46-7 4-[[(2R,3S,5R)-3-[(2-Cyano-ethoxy)-diisopropylamino-phosphanyloxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-bis-(4-methoxy-phenyl)-methyl]-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 132454-42-3 4-[[(2R,3S,5R)-3-Hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-bis-(4-methoxy-phenyl)-methyl]-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester 

Relevant academic research and scientific papers

Acid labile immunoconjugate intermediates

Trityl derivatives useful as "linkers" for preparation of imunoconjugates comprising drugs end antibodies are provided. Immunoconjugates and processes for their preparation and use are also provided. This invention also provides for prodrugs comprising a

Succinimidyl trityl compounds and a process for preparing same

The invention pertains to compounds and methods for the reversible modification of natural products, biopolymers or synthons for natural products or biopolymers, such as nucleosides, nucleotides, and oligonucleosides. The modification enables one to perfo

Heterobifunctional Trityl Derivatives as Linking Reagents for the Recovery of Nucleic Acids after Labeling and Immobilization

The synthesis of two heterobifunctional 4,4'-dimethoxytrityl derivatives carrying a N-hydroxysuccinic acid group as active ester in para 5a or meta position 5b is described.While 5a has been synthesized previously via six steps a novel and more efficient four step synthesis for both compounds is introduced here.The meta compound 5b provides for a more acid labile trityl ether linkage compared to the para derivative 5a.Using these compounds as linking agents biopolymers in particular nucleic acids can easily be recovered after labeling or immobilization by treatment with a mild acid such as 80percent aqueous acetic acid.

A versatile acid-labile linker for modification of synthetic biomolecules

A triphenylmethyl protecting group/linker suitable for automated labeling of synthetic biopolymers is described. The method is unique since the protecting group/linker may be removed to give the unmodified biomolecule.