132464-83-6

Basic information

• Product Name: 5-Iodoindane
• Synonyms: 5-iodoindane;1H-Indene, 2,3-dihydro-5-iodo-;5-iodo-2,3-dihydro-1H-indene
• CAS NO: 132464-83-6
• Molecular Formula: C₉H₉I
• Molecular Weight: 244.07
• Mol File: 132464-83-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Iodoindane(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Iodoindane(132464-83-6)
• EPA Substance Registry System: 5-Iodoindane(132464-83-6)

Safety Data

• Hazardous Substances Data: 132464-83-6(Hazardous Substances Data)

Upstream product

• 24425-40-9 indan-5-amine 

Downstream Products

• 5453-98-5 indan-5-yl acetic acid 
• 132464-80-3 4-(2-Chloro-phenyl)-2-(2-indan-5-yl-ethyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene 
• 132464-76-7 4-(2-Chloro-phenyl)-2-((Z)-2-indan-5-yl-vinyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene 
• 132464-86-9 5-ethynyl-2,3-dihydro-1H-indene 

Relevant articles and documents

Discovery of indane propanamides as potent and selective TRPV1 antagonists

A series of indane-type acetamide and propanamide analogues were investigated as TRPV1 antagonists. The analysis of structure–activity relationship indicated that indane A-region analogues exhibited better antagonism than did the corresponding 2,3-dihydrobenzofuran and 1,3-benzodioxole surrogates. Among them, antagonist 36 exhibited potent and selective antagonism toward capsaicin for hTRPV1 and mTRPV1. Further, in vivo studies indicated that antagonist 36 showed excellent analgesic activity in both phases of the formalin mouse pain model and inhibited the pain behavior completely at a dose of 1 mg/kg in the 2nd phase.