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132464-83-6

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132464-83-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 132464-83-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,4,6 and 4 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 132464-83:
(8*1)+(7*3)+(6*2)+(5*4)+(4*6)+(3*4)+(2*8)+(1*3)=116
116 % 10 = 6
So 132464-83-6 is a valid CAS Registry Number.

132464-83-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-iodo-2,3-dihydro-1H-indene

1.2 Other means of identification

Product number -
Other names 2,3-dihydro-5-iodo-1H-indene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:132464-83-6 SDS

132464-83-6Upstream product

132464-83-6Relevant articles and documents

Discovery of indane propanamides as potent and selective TRPV1 antagonists

Ahn, Songyeon,Kim, Yong Soo,Kim, Myeong Seup,Ann, Jihyae,Ha, Heejin,Yoo, Young Dong,Kim, Young Ho,Blumberg, Peter M.,Frank-Foltyn, Robert,Bahrenberg, Gregor,Stockhausen, Hannelore,Christoph, Thomas,Lee, Jeewoo

, (2020/01/03)

A series of indane-type acetamide and propanamide analogues were investigated as TRPV1 antagonists. The analysis of structure–activity relationship indicated that indane A-region analogues exhibited better antagonism than did the corresponding 2,3-dihydrobenzofuran and 1,3-benzodioxole surrogates. Among them, antagonist 36 exhibited potent and selective antagonism toward capsaicin for hTRPV1 and mTRPV1. Further, in vivo studies indicated that antagonist 36 showed excellent analgesic activity in both phases of the formalin mouse pain model and inhibited the pain behavior completely at a dose of 1 mg/kg in the 2nd phase.

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