132464-89-2

Upstream product

• 2221-00-3 4-(N-imidazolyl)aniline 
• 288-32-4 1H-imidazole 
• 589-87-7 1,4-bromoiodobenzene 
• 624-38-4 para-diiodobenzene 
• 50-00-0 formaldehyd 
• 540-37-4 p-aminoiodobenzene 

Downstream Products

• 957070-47-2 1,8-bis(imidazolylphenyl)anthracene 
• 957070-51-8 4,5-bis(imidazolylphenyl)-9,9-dimethylxanthene 
• 132464-78-9 4-(2-Chloro-phenyl)-2-[2-(4-imidazol-1-yl-phenyl)-ethyl]-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene 
• 1367528-40-2 C₁₂H₈N₄ 
• 1434057-23-4 1-(4-iodophenyl)-3-phenyl-1H-imidazol-3-ium tetrafluoroborate 

Relevant academic research and scientific papers

Microwave-promoted N-arylation of imidazole and amino acids in the presence of Cu2O and CuO in poly(ethylene glycol)

Copper(I)-catalyzed N-arylation of imidazole with iodobenzene, its derivatives, and bromobenzene in poly(ethylene glycol) under microwave irradiation was studied. The influence of the following factors on the yield of arylation product was investigated: the nature of the source of copper and ligand, type of poly(ethylene glycol) (PEG) used, and substituents in iodoarene. An optimal catalytic system was selected: CuO/l-Hys/Cs2CO3/PEG-400, a possibility of recycling of copper-containing catalyst was demonstrated. N-Arylation of eight natural amino acids using catalysis with Cu2O/Cs2CO3/PEG-400 and microwave irradiation was studied, the dependence of the reaction results on temperature, duration of the process, and the ratio of the starting reagents was found. The highest yields of the target products were reached in the case of leucine, valine, and phenylalanine.

The use of C1 symmetry imidazole-carboxylate building block and auxiliary acetate co-ligand for assembly of a 2D wave-like zinc(II) coordination polymer: experimental and theoretical study

We report the synthesis and characterization of a two-dimensional Zn(II) coordination polymer employing a ligand with a biphenyl core containing imidazole and carboxylate groups in the presence of acetate moieties as bridging molecules. The obtained [ZnLA

Spontaneous resolution of non-centrosymmetric coordination polymers of zinc(II) with achiral imidazole-biphenyl-carboxylate ligands

A convenient synthesis and a full characterization of imidazole- and benzimidazole-biphenyl-carboxylic acid ligands and two zinc coordination polymers are presented. The crystal structure of two precursors 1-(4-iodo-phenyl)-1H-imidazole (1), 1-(4-iodophen

Novel lanthanide (III) complexes derived from an imidazole–biphenyl–carboxylate ligand: Synthesis, structure and luminescence properties

A series of neutral mononuclear lanthanide complexes [Ln(HL)2 (NO3)3] (Ln = La, Ce, Nd, Eu, Gd, Dy, Ho) with rigid bidentate ligand, HL (4′-(1H-imidazol-1-yl)biphenyl-4-carboxylic acid) were synthesized under so

Cross-coupling of phenyl halides with sodium dicyanomethanide in the presence of Tetrakis(triphenyphosphine)palladium

1-Aromatic substituted imidazoles were synthesized by a convenient modified process. A cross-coupling reaction of phenyl halides with sodium dicyanomethanide has been achieved to produce the arylmalononitriles coupling products as zwitterionic precursors

An Ullmann coupling of aryl iodides and amines using an air-stable diazaphospholane ligand

(Chemical Equation Presented) A copper-based catalytic system, using an air-stable diazaphospholane as the ligand, was developed for an efficient Ullmann reaction between aryl iodides and alkyl or heterocyclic amines.

Copper-catalyzed N-arylation of imidazoles and benzimidazoles

(Chemical Equation Presented) 4,7-Dimethoxy-1,10-phenanthroline (L1c) was found to be an efficient ligand for the copper-catalyzed N-arylation of imidazoles and benzimidazoles with both aryl iodides and bromides under mild conditions. Further optimization of the system has revealed that the addition of poly(ethylene glycol) accelerates this reaction. A variety of hindered and functionalized imidazoles, benzimidazoles, and aryl halides were transformed in good to excellent yields. Heteroaryl halides were also coupled in moderate to good yields. We also present the results obtained from a series of coupling reactions, which directly compare the use of L1c with other recently reported ligands.

Thienotriazolodiazepines as platelet-activating factor antagonists. Steric limitations for the substituent in position 2

The preparations of thienotriazolodiazepines bearing a substituted ethynyl group at the 2-position, and the corresponding cis-olefins and fully saturated analogues are described. The compounds were evaluated as potential antagonists of platelet-activating