132532-07-1

Basic information

• Product Name: [1,1'-binaphthalen]-2-yldiphenylphosphine oxide
• Synonyms: [1,1'-binaphthalen]-2-yldiphenylphosphine oxide
• CAS NO: 132532-07-1
• Molecular Weight: 454.508
• Mol File: 132532-07-1.mol

Chemical Properties

• CAS DataBase Reference: [1,1'-binaphthalen]-2-yldiphenylphosphine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-binaphthalen]-2-yldiphenylphosphine oxide(132532-07-1)
• EPA Substance Registry System: [1,1'-binaphthalen]-2-yldiphenylphosphine oxide(132532-07-1)

Safety Data

• Hazardous Substances Data: 132532-07-1(Hazardous Substances Data)

Upstream product

• 132532-08-2 (R)-(+)-diethyl 2-(1,1'-binaphthyl)phosphonate 
• 100-58-3 phenylmagnesium bromide 
• 207611-58-3 2-bromo-[1,1']dinaphthyl 
• 676267-05-3 2-bromo-1-iodonaphthalene 
• 13922-41-3 1-Naphthylboronic acid 
• 264188-44-5 (S)-2-diphenylphosphino-1,1'-binaphthyl 
• 90948-03-1 1-bromo-2-iodonaphthalene 
• 1589518-11-5 (1-bromonaphthalen-2-yl)diphenylphosphine oxide 
• 4559-70-0 Diphenylphosphine oxide 
• 35216-79-6 (R)-[1,1'-binaphthalen]-2-ol 
• 128544-05-8 (R)-(-)-1,1'-bi-2-naphthol triflate 
• 24630-80-6 diphenylphosphine oxide 
• 2216-69-5 1-Methoxynaphthalene 
• 1079-66-9 chloro-diphenylphosphine 

Downstream Products

• 132548-91-5 (S)-(+)-2-hydroxy-2'-diphenylphosphinoyl-1,1'-binaphthyl 
• 1602492-96-5 2'-(diphenylphosphoryl)-1,1'-binaphthyl-2-yl acetate 
• 264188-44-5 (S)-2-diphenylphosphino-1,1'-binaphthyl 

Relevant articles and documents

P(O)R2-directed Pd-catalyzed C-H functionalization of biaryl derivatives to synthesize chiral phosphorous ligands

Chiral phosphorus ligands have been widely used in transition metal-catalyzed asymmetric reactions. Herein, we report a new synthesis approach of chiral biaryls containing a phosphorus moiety using P(O)R 2-directed Pd-catalyzed C-H activation; the functionalized products are produced with good enantioselectivity.

Palladium-catalyzed R2(O)P directed C(sp2)-H acetoxylation

A novel and efficient Pd-catalyzed C-H acetoxylation is described. The approach uses R2(O)P as a directing group to synthesize various substituted 2′-phosphorylbiphenyl-2-OAc compounds. Notably, the reaction exhibits smooth operation under mild conditions and shows good functional group tolerance. Products are obtained with high selectivity and yields. This journal is the Partner Organisations 2014.

Pd(II)-catalyzed C(sp2)-H hydroxylation with R 2(O)P-coordinating group

A novel R2(O)P-directed Pd(II)-catalyzed C-H hydroxylation to synthesize various substituted 2′-phosphorylbiphenyl-2-ol compounds is described. Notably, the reaction operates under mild conditions and shows good functional group tolerance, high selectivity, and yield.

Nucleophilic aromatic substitution reactions of 1-methoxy-2- (diphenylphosphinyl)naphthalene with C-, N-, and O-nucleophiles: Facile synthesis of diphenyl(1-substituted-2-naphthyl)phosphines

A novel nucleophilic aromatic substitution reaction is described in which the methoxy group of 1-methoxy-2-(diphenylphosphinyl)-naphthalene is readily replaced with Grignard reagents, alkoxides, and amides. Reduction of the resulting phosphine oxides provides a convenient route to diphenyl(1- substituted-2-naphthyl)phosphines.

Preparation of optically active binaphthylmonophosphines (MOP's) containing various functional groups

Optically active 2'-diphenylphosphino-1,1'-binaphthyls (MOP's) having various functional groups, cyano, aminomethyl, methoxycarbonyl, carboxy, and hydroxymethyl, at the C2-position were prepared. A cyano group was introduced on the MOP skeleton by nickel-

Stereospecific functionalization of (R)-(-)-1,1'-BI-2-naphthol triflate

Several examples of transition metal mediated functionalization of chiral 1,1'-bi-2-naphthol triflate are described which proceed with complete retention of substrate chirality. The transformation described demonstrate the potential of Pd(0) mediated reactions for the stereoselective transformation of the C-O bonds in this substrate.