132540-67-1Relevant academic research and scientific papers
Double asymmetric induction as a mechanistic probe: The doubly diastereoselective conjugate addition of enantiopure lithium amides to enantiopure α,β-unsaturated esters and enantiopure α,β-unsaturated hydroxamates
Davies, Stephen G.,Lee, James A.,Roberts, Paul M.,Thomson, James E.,Yin, Jingda
experimental part, p. 6382 - 6403 (2011/09/19)
The doubly diastereoselective conjugate addition of the antipodes of lithium N-benzyl-N-(α-methylbenzyl)amide to a range of enantiopure α,β-unsaturated esters [derived from Corey's 8-phenylmenthol chiral auxiliary] and enantiopure α,β-unsaturated hydroxamates [derived from our 'chiral Weinreb amide' auxiliary (S)-N-1-(1′-naphthyl)ethyl-O-tert- butylhydroxylamine] has been used as a mechanistic probe to determine the reactive conformations of these acceptors.
Efficient EPC Synthesis of β-Aminobutanoic Acid
Gmeiner, Peter
, p. 501 - 502 (2007/10/02)
A practical approach to enantiomerically pure (R)-3-aminobutanoic acid (6) from L-asparagine is presented.The key step of the synthesis is the chemoselective reduction of the β-homoserine derivative 2.
