132554-22-4Relevant academic research and scientific papers
SiCl4-catalyzed/PR3-mediated β-C(sp3)?H functionalization of nitrones to α,β-unsaturated imines and aromatic heterocycles
Zhu, De-Ping,Xu, Bao-Hua,Du, Yi-Ran,Zhang, Suo-Jiang
, p. 2230 - 2238 (2018)
A novel method of SiCl4-catalyzed/PR3-mediated β-C(sp3)?H functionalization of nitrones with aldehydes/ketones to α,β-unsaturated imines was developed. The synthesis of α,β-unsaturated imines mainly invovles deoxygenation and aldol condensation, each proceeding under a cooperation effect between Lewis acid and Lewis base. In addition, both the acidity and hydrolytic stability of the weak SiCl4 were supposed to be enhanced by coordination with phosphine oxide (R = Et) or phosphoric triamide (R = NMe2) that originated from deoxygenation of nitrones by PR3. In the case of 6-membered nitrone, a [1,3]-hydride shift within the resulted α,β-unsaturated imines renders the aromatization leading to 3,5-dialkylpyridines.
REACTIONS OF N-(4-METHOXYBENZYLIDENE)-N,N-DIALKYLIMINIUM AND 2-(4-METHOXYPHENYL)PYRIDINIUM SALTS WITH ALIPHATIC AMINES
Blokhin, A. V.,Tyurekhodzhaeva, M. A.,Bazhenov, D. V.,Bobrovskii, S. I.,Bundel', Yu. G.
, p. 1022 - 1025 (2007/10/02)
The reaction of 4-methoxybenzylideneiminium salts with methylamine and dimethylamine on heating results in replacement of the MeO group by an alkylamino-group, whereas the reaction with piperidine affords 3,5-bis-(4-methoxybenzyl)pyridine.N-Methyl-2-(4-me
