132560-66-8 Usage
General Description
1-Propanone, 2-chloro-1-(4-ethylphenyl)- (9CI) is a chemical compound with the molecular formula C10H11ClO. It is also known by its IUPAC name 2-chloro-1-(4-ethylphenyl)propan-1-one. 1-Propanone, 2-chloro-1-(4-ethylphenyl)- (9CI) is a chlorinated ketone, which is commonly used in organic synthesis and as an intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is a colorless liquid with a strong odor and is considered to be a hazardous substance due to its potential health effects such as skin and eye irritation, as well as its flammability. Additionally, it is important to handle and store this chemical with proper safety precautions to avoid any accidents or harm to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 132560-66-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,5,6 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 132560-66:
(8*1)+(7*3)+(6*2)+(5*5)+(4*6)+(3*0)+(2*6)+(1*6)=108
108 % 10 = 8
So 132560-66-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H13ClO/c1-3-9-4-6-10(7-5-9)11(13)8(2)12/h4-8H,3H2,1-2H3
132560-66-8Relevant articles and documents
Photochemical Rearrangement of α-Chloro-Propiophenones to α-Arylpropanoic Acids: Studies on Chirality Transfer and Synthesis of (S)-(+)-Ibuprofen and (S)-(+)-Ketoprofen
Sonawane, Harikisan,Bellur, Nanjundiah S.,Kulkarni, Dilip G.,Ayyangar, Nagaraj R.
, p. 1243 - 1260 (2007/10/02)
A new single-step efficient photochemical approach for α-arylpropanoic acids (4) from α-chloro-propiophenones (5) is described.It involves carbonyl triplet excited state directed 1,2-aryl migration of the aryl group which has been found to be highly dependent upon the nature of the aryl substituent.The mode of the rearrangement is probed by the study of the photobehaviour of a set of optically active α-chloro-propiophenones.The results suggest that the nature of the carbonyl triplets (n, ?*/ ?, ?*) plays an important role in the chirality transfer.This method finds application in the synthesis of optically active ibuprofen (4e) and ketoprofen (26), though in moderate optical yields.