132560-67-9 Usage
Synonym
4'-propylacetophenone
+ Physical state
Liquid
+ Appearance
Colorless to pale yellow liquid
+ Molecular weight
212.7 g/mol
+ Boiling point
299-301°C (574-578°F)
+ Melting point
Not applicable (decomposes)
+ Solubility
Slightly soluble in water, miscible with organic solvents
+ Functional groups
Ketone, chloro, alkyl
+ Aromatic ring
Phenyl group with a propyl group attached at the 4-position
Uses
+ Intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds
+ Flavoring agent and fragrance in the food and cosmetic industries
Hazards
+ Classified as a hazardous substance
+ Potential harmful effects on human health and the environment
+ Handling precautions are necessary
Check Digit Verification of cas no
The CAS Registry Mumber 132560-67-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,5,6 and 0 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 132560-67:
(8*1)+(7*3)+(6*2)+(5*5)+(4*6)+(3*0)+(2*6)+(1*7)=109
109 % 10 = 9
So 132560-67-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H15ClO/c1-3-4-10-5-7-11(8-6-10)12(14)9(2)13/h5-9H,3-4H2,1-2H3
132560-67-9Relevant articles and documents
Photochemical Rearrangement of α-Chloro-Propiophenones to α-Arylpropanoic Acids: Studies on Chirality Transfer and Synthesis of (S)-(+)-Ibuprofen and (S)-(+)-Ketoprofen
Sonawane, Harikisan,Bellur, Nanjundiah S.,Kulkarni, Dilip G.,Ayyangar, Nagaraj R.
, p. 1243 - 1260 (2007/10/02)
A new single-step efficient photochemical approach for α-arylpropanoic acids (4) from α-chloro-propiophenones (5) is described.It involves carbonyl triplet excited state directed 1,2-aryl migration of the aryl group which has been found to be highly dependent upon the nature of the aryl substituent.The mode of the rearrangement is probed by the study of the photobehaviour of a set of optically active α-chloro-propiophenones.The results suggest that the nature of the carbonyl triplets (n, ?*/ ?, ?*) plays an important role in the chirality transfer.This method finds application in the synthesis of optically active ibuprofen (4e) and ketoprofen (26), though in moderate optical yields.
