132573-80-9Relevant academic research and scientific papers
Nucleophilic Substitution in Benzylic Phosphonamidothioic Chlorides: Influence of Substituents on the Elimination-Addition Pathway
Harger, Martin J. P.,Hurman, Barbara T.
, p. 490 - 491 (2007/10/03)
The elimination-addition pathway that competes with SN2(P) in the reaction of ArCH2P(S)(NMe2)CI with Et2NH is very sensitive to the acidity of the benzylic C - H bond (p 3.45).
Nucleophilic Substitution in Benzylic Thiophosphinyl and Thiophosphonyl Chlorides: the Contribution of Elimination-Addition Pathways with Methylenethiooxophosphorane (Thiophosphene) Intermediates
Coogan, Michael P.,Harger, Martin J. P.
, p. 2101 - 2108 (2007/10/02)
For the reactions of ArCH2P(S)(Ph)Cl and ArCH2P(S)(NMe2)Cl with Et2NH, changing ArCH2 from benzyl to 4-nitrobenzyl increases the rates of substitution by factors of 80 and >103, respectively, and reduces markedly the ability to discriminate bet
