132575-67-8

Upstream product

• 132575-65-6 3-hydrazino-4,5,6-triphenylpyridazine 
• 103-72-0 phenyl isothiocyanate 
• 95161-23-2 4,5,6-triphenylpyridazine-3(2H)-thione 
• 132575-72-5 3-methylthio-4,5,6-triphenylpyridazine 
• 132575-64-5 3-chloro-4,5,6-triphenylpyridazine 
• 31590-01-9 4,5,6-triphenyl-3(2H)-pyridazinone 
• 876465-56-4 1-(4,5,6-triphenylpyridazin-3-yl)-4-phenylthiosemicarbazide 

Relevant academic research and scientific papers

Pyridazine derivatives and related compounds, part 8: Synthesis of different heterocycles from 3-hydrazinopyridazine

The reaction of 3-hydrazino-4,5,6-triphenylpyridazine 1 with phenylisothiocyanate in ethanol gave thiocarbamoylhydrazine 2 while in butanol gave triazolo[4,3-b]pyridazinethione 3. Reaction of 1 with ethyl chloroformate gave ethoxycarbamoylhydrazinopyridazine 5 which upon heating it furnished triazolopyridazine 6. Also, the reaction of 1 with chloroacetylchloride gave triazolopyridazine 7. Reaction of 1 with a number of aromatic aldehydes, D-glucose, and pyruvic acid gave the corresponding hydrazones 9,11. Oxidative cyclization of 9a,b gave triazolo[4,3-b]pyridazine 10a,b. On the other hand, reactions of 1 with diethyl oxalate, ethyl acetoacetate, acetylacetone, ethyl cyanoacetate, diacetyl, and with phthalic anhydride are also reported.