132605-96-0

Basic information

• Product Name: Boc-(R)-2-(aMinoMethyl)-4-Methylpentanoic acid
• Synonyms: Boc-(R)-2-(aMinoMethyl)-4-Methylpentanoic acid;(Tert-Butoxy)Carbonyl (R)-2-(Aminomethyl)-4-methylpentanoic acid;Pentanoic acid,2-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-4-methyl-, (2R)-
• CAS NO: 132605-96-0
• Molecular Formula: C12H23NO4
• Molecular Weight: 245.31532
• Mol File: 132605-96-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 74 °C(Solv: ethyl ether (60-29-7); pentane (109-66-0))
• Boiling Point: 374.3±25.0 °C(Predicted)
• Appearance: /
• Density: 1.046±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.49±0.21(Predicted)
• CAS DataBase Reference: Boc-(R)-2-(aMinoMethyl)-4-Methylpentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-(R)-2-(aMinoMethyl)-4-Methylpentanoic acid(132605-96-0)
• EPA Substance Registry System: Boc-(R)-2-(aMinoMethyl)-4-Methylpentanoic acid(132605-96-0)

Safety Data

• Hazardous Substances Data: 132605-96-0(Hazardous Substances Data)

Usage

General Description

Boc-(R)-2-(aminomethyl)-4-methylpentanoic acid is a chemical compound commonly used in organic synthesis and pharmaceutical research. It is a derivative of the amino acid valine, with a tert-butoxycarbonyl (Boc) protecting group attached to the amino group. Boc-(R)-2-(aMinoMethyl)-4-Methylpentanoic acid is often employed as a building block in the preparation of peptide and protein-based drugs, as well as in the synthesis of other complex organic molecules. Its chiral nature, with a stereocenter at the R position, makes it useful for the production of enantiopure compounds. Boc-(R)-2-(aminomethyl)-4-methylpentanoic acid is also known for its stability and compatibility with a wide range of chemical reactions, making it a valuable tool in organic synthesis and drug discovery.

Upstream product

• 887143-14-8 (2S)-N-{(2R)-2-[(dibenzylamino)methyl]-4-methylpentanoyl}camphorsultam 
• 24424-99-5 di-tert-butyl dicarbonate 
• 887143-09-1 methyl 2-[(dibenzylamino)methyl]-4-methylpentanoate 
• 776327-14-1 2-aminomethyl-4-methyl-pentanoic acid methyl ester 
• 100869-07-6 2-(aminomethyl)-4-methylpentanoic acid 
• 927830-83-9 (R)-2-Aminomethyl-1-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-4-methyl-pentan-1-one 
• 887143-13-7 (S)-N-(2-bromo-4-methyl-pentanoyl) camphorsultam 
• 210345-89-4 (2R)-([amino]methyl)-4-methylpentanoic acid 
• 114438-66-3 (-)-methyl-(S)-2-bromo-4-methylpentanoate 
• 28659-87-2 (S)-2-bromo-4-methylpentanoic acid 
• 61-90-5 L-leucine 
• 262301-37-1 N-[3-(N'-diphenylmethylene)-2-isobutylaminopropionyl] sultam 
• 941292-90-6 (S)-β-2-methylpropyl-γ-Boc-amino-propylalcohol 
• 106367-47-9 Methyl 4-methyl-2-cyanopent-2-enoate 

Relevant articles and documents

Beta amino acid-modified and fluorescently labelled kisspeptin analogues with potent KISS1R activity

Kisspeptin analogues with improved metabolic stability may represent important ligands in the study of the kisspeptin/KISS1R system and have therapeutic potential. In this paper we assess the activity of known and novel kisspeptin analogues utilising a du

Practical synthesis of enantiomerically pure β2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes

Proline-catalyzed diastereoselective aminomethylation of aldehydes using a chiral iminium ion, generated from a readily prepared precursor, provides α-substituted-β-amino aldehydes with 85:15 to 90: 10 dr. The α-substituted-β-amino aldehydes can be reduce

New scalable asymmetric aminomethylation reaction for the synthesis of β2-amino acids

β-Amino acids are useful tools in the design of peptidomimetics, and the development of new methods for their syntheses, particularly the synthesis of β2-amino acids, remains an important challenge. Here we report a new scalable route based on the aminomethylation of silyl ketene N,O-acetals by Mannich-type iminium electrophiles. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.