13262-51-6Relevant academic research and scientific papers
Highly Regioselective Iodination of N-Phenylureas with Iodine/Trichloroisocyanuric Acid
Sanabria, Carlos M.,do Casal, Mariana T.,De Souza, Raphael B. A.,De Aguiar, Lúcia C. S.,De Mattos, Marcio C. S.
, p. 1648 - 1654 (2017)
An efficient regioselective iodination of N-phenylureas was developed using iodine/trichloroisocyanuric acid in acetonitrile at room temperature. This protocol proved to be effective on a broad range of substituted N-phenylureas, forming the p-iodinated compounds in 65-96% yield under mild and neutral conditions.
The impact of modular substitution on crystal packing: The tale of two ureas
Koshti, Vijay S.,Thorat, Shridhar H.,Gote, Ravindra P.,Chikkali, Samir H.,Gonnade, Rajesh G.
, p. 7078 - 7094 (2016/10/03)
A small library of 13 (3a-m) compounds with modular positioning of iodide and urea/thiourea groups was synthesized in excellent yields in a single step synthetic protocol. The existence of the anticipated (thio)urea derivatives was unambiguously establish
THE INTRAMOLECULAR NH...Cl HYDROGEN BOND IN UREA DERIVATIVES CONTAINING THE o-CHLOROPHENYL GROUP
Mido, Yoshiyuki,Okuno, Tomoko
, p. 29 - 34 (2007/10/02)
The solution ν(N-H) vibrations of various disubstituted ureas containing a halophenyl group have been examined in order to directly confirm the presence of an intramolecular NH...Cl hydrogen bond in the o-chloro analog.In chlorophenyl derivatives the ν(N-
