1326705-18-3

Basic information

• Product Name: (1S,2S)-N-(4-cyanophenyl)-1-phenyl-2-(methylsulfenyl)-2-{2-[(S)-p-tolylsulfinyl]phenyl}ethylamine
• Synonyms: (1S,2S)-N-(4-cyanophenyl)-1-phenyl-2-(methylsulfenyl)-2-{2-[(S)-p-tolylsulfinyl]phenyl}ethylamine
• CAS NO: 1326705-18-3
• Molecular Weight: 482.67
• Mol File: 1326705-18-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2S)-N-(4-cyanophenyl)-1-phenyl-2-(methylsulfenyl)-2-{2-[(S)-p-tolylsulfinyl]phenyl}ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-N-(4-cyanophenyl)-1-phenyl-2-(methylsulfenyl)-2-{2-[(S)-p-tolylsulfinyl]phenyl}ethylamine(1326705-18-3)
• EPA Substance Registry System: (1S,2S)-N-(4-cyanophenyl)-1-phenyl-2-(methylsulfenyl)-2-{2-[(S)-p-tolylsulfinyl]phenyl}ethylamine(1326705-18-3)

Safety Data

• Hazardous Substances Data: 1326705-18-3(Hazardous Substances Data)

Upstream product

• 852332-84-4 (S)-α-(methylsulfenyl)-2-(p-tolylsulfinyl)toluene 
• 17224-21-4 1-(4-cyanophenyl)-N-phenylmethanimine 
• 100-52-7 benzaldehyde 
• 873-74-5 4-Aminobenzonitrile 

Downstream Products

• 1326705-25-2 (1S,2S)-N-(4-cyanophenyl)-2-(methylsulfenyl)-1,2-diphenylethylamine 
• 1326705-26-3 (1R)-N-(4-cyanophenyl)-1,2-diphenylethylamine 

Relevant articles and documents

Synthesis of optically pure vic-sulfanyl amines mediated by a remote sulfinyl group

Enantiomerically pure syn-1,2-diaryl-1,2-sulfanylamine derivatives can be obtained in a completely stereoselective manner by reaction of the benzylcarbanion Li-(S)-1 with N-phenyl (or PMP)-arylidene aldimines and further desulfinylation with t-BuLi. Theoretical studies at the DFT (mPW1PW91) level with the CPCM model, by using the Gaussian09 program, provide a good explanation for the stereochemical results.