1326708-06-8Relevant articles and documents
Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of hedgehog signaling based on cyclopamine
Zhang, Zhihui,Baubet, Valerie,Ventocilla, Christian,Xiang, Chaomei,Dahmane, Nadia,Winkler, Jeffrey D.
, p. 4786 - 4789 (2011)
Previous work in this laboratory established that the readily available F-ring aromatic analog of cyclopamine is a highly potent inhibitor of Hedgehog signaling. The synthesis and biological evaluation of two F-ring saturated analogs that are more potent