1326775-02-3

Upstream product

• 110-93-0 6-Methyl-hept-5-en-2-on 
• 16475-90-4 estere metilico dell'acido 5-acetilsalicilico 

Downstream Products

• 1326774-98-4 5-(1',3'-dihydroxy-3',7'-dimethyloct-6'-en-1'-yl)-2-hydroxybenzoic acid methyl ester 
• 1326775-03-4 5-(1',3'-dihydroxy-3',7'-dimethyl-oct-6'-en-1'-yl)-2-hydroxybenzoic acid 
• 1326774-99-5 2-hydroxy-5-(3'-hydroxy-3',7'-dimethyloct-6'-enoyl)benzoic acid 

Relevant academic research and scientific papers

Enantioselective total synthesis and absolute configuration of the alleged structure of crassinervic acid

An enantioselective synthesis of the structure reported for the natural antifungal compound, (-)-crassinervic acid (1), has been achieved starting from geraniol and p-hydroxybenzoic acid. The key chirality-inducing step is a Sharpless asymmetric epoxidation of an allylic alcohol, on the basis of which the S configuration can be assigned to the (-) natural enantiomer. The discrepancies between the spectroscopic data for synthetic and natural crassinervic acid cast some doubts on the structure assigned to the natural compound. A possible revised structure is discussed.