13268-91-2Relevant academic research and scientific papers
Preparation of β-substituted γ-keto esters by the grignard reaction on N-acylpyrazoles
Kashima, Choji,Shirahata, Yoshie,Tsukamoto, Yoshihiro
, p. 309 - 317 (2001)
Various γ-keto esters were prepared by either the alcoholysis of N-(4-oxoalkanoyl)pyrazoles or the Grignard replacement of pyrazole moiety of 4-(N-pyrazolyl)-4-oxoalkanoic esters. By using 3-phenyl-ι-menthopyrazole as a chiral auxiliary, β-substituted γ-keto esters were enantioselectively obtained.
