132683-32-0Relevant articles and documents
Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4)
Day, Jonathan P.,Lindsay, Barbara,Riddell, Tracy,Jiang, Zhong,Allcock, Robert W.,Abraham, Achamma,Sookup, Sebastian,Christian, Frank,Bogum, Jana,Martin, Elisabeth K.,Rae, Robert L.,Anthony, Diana,Rosair, Georgina M.,Houslay, Daniel M.,Huston, Elaine,Baillie, George S.,Klussmann, Enno,Houslay, Miles D.,Adams, David R.
, p. 3331 - 3347 (2011/07/09)
Figure Presented. A survey of PDE4 inhibitors reveals that some compounds trigger intracellular aggregation of PDE4A4 into accretion foci through association with the ubiquitin-binding scaffold protein p62 (SQSTM1). We show that this effect is driven by i
PYRROLIDONES WITH ANTI-HIV ACTIVITY
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Page 67, (2008/06/13)
The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhi