957770-89-7

Basic information

• Product Name: (3R)-4-methoxyphenyl 3-(3-(benzyloxy)-4-methoxyphenyl)-4-nitrobutanethioate
• Synonyms: (3R)-4-methoxyphenyl 3-(3-(benzyloxy)-4-methoxyphenyl)-4-nitrobutanethioate
• CAS NO: 957770-89-7
• Molecular Weight: 467.543
• Mol File: 957770-89-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R)-4-methoxyphenyl 3-(3-(benzyloxy)-4-methoxyphenyl)-4-nitrobutanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: (3R)-4-methoxyphenyl 3-(3-(benzyloxy)-4-methoxyphenyl)-4-nitrobutanethioate(957770-89-7)
• EPA Substance Registry System: (3R)-4-methoxyphenyl 3-(3-(benzyloxy)-4-methoxyphenyl)-4-nitrobutanethioate(957770-89-7)

Safety Data

• Hazardous Substances Data: 957770-89-7(Hazardous Substances Data)

Upstream product

• 63909-29-5 (E)-2-(benzyloxy)-1-methoxy-4-(2-nitrovinyl)benzene 
• 428442-20-0 3-[(4-methoxyphenyl)sulfanyl]-3-oxopropanoic acid 

Downstream Products

• 132683-32-0 (R)-4-(3-hydroxy-4-methoxyphenyl)pyrrolidin-2-one 

Relevant articles and documents

Mimicry of polyketide synthases - Enantioselective 1,4-addition reactions of malonic acid half-thioesters to nitroolefins

Bifunctionality is the key for mimicking the active site of polyketide synthases with synthetic metal-free organocatalysts (see picture). Cinchona alkaloid derivatives bearing both a basic site and a urea moiety catalyze conjugate enantioselective addition reactions of malonic acid half thioesters (MAHTs) to nitroolefins with up to quantitative yields and selectivities up to 90% ee. (Chemical Equation Presented).