132688-31-4 Usage
Description
1-(2,6-dimethylphenyl)-1H-pyrrole-3-carbaldehyde is an organic compound characterized by its unique molecular structure, featuring a pyrrole ring with a formyl group at the 3-position and a 2,6-dimethylphenyl group attached to it. 1-(2,6-dimethylphenyl)-1H-pyrrole-3-carbaldehyde is known for its potential applications in various fields due to its chemical properties.
Uses
Used in Pharmaceutical Industry:
1-(2,6-dimethylphenyl)-1H-pyrrole-3-carbaldehyde is used as a key intermediate in the synthesis of pyrrolyl-substituted hydroxamic acids. These hydroxamic acids serve as lipoxygenase inhibitors, which are important in the development of drugs targeting various inflammatory and allergic conditions. The compound's role in this application is to provide a structural framework that can be further modified to enhance the potency and selectivity of the resulting lipoxygenase inhibitors.
Check Digit Verification of cas no
The CAS Registry Mumber 132688-31-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,6,8 and 8 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 132688-31:
(8*1)+(7*3)+(6*2)+(5*6)+(4*8)+(3*8)+(2*3)+(1*1)=134
134 % 10 = 4
So 132688-31-4 is a valid CAS Registry Number.
132688-31-4Relevant articles and documents
Direct and efficient synthesis of pyrrole-3-carbaldehydes by Vilsmeier-Haack formylation of pyrroles with sterically crowded amides
Ilyin, Petrv.,Pankova, Alenas.,Kuznetsov, Mikhail A.
, p. 1353 - 1358 (2012)
A simple and convenient synthetic method to prepare N-substituted pyrrole-3-carbaldehydes by Vilsmeier-Haack formylation of pyrroles using sterically crowded formamides was developed. The dependence of the formylation regioselectivity on steric features of substrates and reagents is discussed. Georg Thieme Verlag Stuttgart · New York.
