13271-68-6

Usage

Uses

Used in Pharmaceutical Industry:
2-Furyldimethylsilane is used as a building block for the synthesis of various organic compounds, particularly in the production of pharmaceuticals. Its unique properties and reactivity contribute to the development of new drugs and medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Furyldimethylsilane serves as a key component in the synthesis of various agrochemicals. Its role in creating effective and innovative products is vital for agricultural advancements.
Used as a Reagent in Organic Reactions:
2-Furyldimethylsilane is utilized as a reagent in the preparation of sila-heterocycles, which are important in various chemical applications. Its ability to participate in cross-coupling reactions in organometallic chemistry further expands its utility in organic synthesis.

InChI:InChI=1/C6H10OSi/c1-8(2)6-4-3-5-7-6/h3-5,8H,1-2H3

Upstream product

• 2786-02-9 2-lithiofuran 
• 1066-35-9 dimethylmonochlorosilane 
• 109-72-8 n-butyllithium 
• 1578-31-0 tri(2-furyl)methylsilane 
• 90185-40-3 [2-(4,5-dihydrofuryl)]dimethylsilane 
• 110-00-9 furan 
• 2786-07-4 2-thienyl lithium 

Downstream Products

• 871938-43-1 (1S,2R,3S,4S,7S)-7-Benzyloxymethyl-3-(furan-2-yl-dimethyl-silanyl)-5-oxo-bicyclo[2.2.2]octane-2-carboxylic acid methyl ester 
• 63366-68-7 1-[2-(furan-2-yl-dimethyl-silanyl)-ethyl]-2,8,9-trioxa-5-aza-1-sila-bicyclo[3.3.3]undecane 

Relevant academic research and scientific papers

ULTRASOUND-INDUCED HETEROGENEOUS REDUCTION OF HALO, ALKOXY AND AMINO DERIVATIVES OF GROUP IVB ELEMENTS WITH LITHIUM ALUMINIUM HYDRIDE

Hydrides of group IVB elements have been prepared in high yield by heterogeneous reduction of the corresponding halo, alkoxy and amino derivatives using lithium aluminium hydride in non-polar solvents under ultrasonic irradiation.

Reactions of heteroarylhydrosilanes with dichlorocarbene under phase-transfer conditions

The reactions of dimethyl(2-thienyl)-, methyl-, tri(2-thienyl)- and dimethyl(2-furyl)silanes (I-IV, respectively) with dichlorocarbene generated from sodium trichloroacetate under solid-liquid phase-transfer conditions afford the corresponding dichloromethylsilanes in 38-66percent yield.The reactivity of the thienylsilanes decreases with the number of electron-accepting thienyl substituents at the silicon atom.Using the competition reactions, the relative rate constants for the reaction of dichlorocarbene insertion into the Si-H bond of thienyl- and furyl-silanes (I and IV) were measured.The reactivity of these silanes was found to be greater than had been expected taking as a basis the Taft ?* constants for the substituent at the silicon atom.This is apparently due to the existence of a p?-d? interaction between the heterocyclic ?-system and the d-orbitals of silicon.

Regiospecific and stereoselective syntheses of (±)-reserpine and (-)-reserpine

Full details of three approaches to an entirely regio- and Stereoselective synthesis of the well-known target reserpine are described, culminating in a total synthesis which efficiently meets these requirements.

Cleavage of Si-C and Ge-C bonds in heterylsilanes and -germanes by organolithium reagents

Organolithium reagents RLi can cleave Si-C and Ge-C bonds in heterylsilanes and -germanes substituting furyl, dihydrofuryl and dihydropyranyl groups for the organolithium residue R.