132723-09-2Relevant articles and documents
Lipophilic, acid-stable, adenosine deaminase-activated anti-HIV prodrugs for central nervous system delivery. 3. 6-amino prodrugs of 2′-β-fluoro-2′,3′-dideoxyinosine
Driscoll, John S.,Siddiqui, Maqbool A.,Ford Jr., Harry,Kelley, James A.,Roth, Jeri S.,Mitsuya, Hiroaki,Tanaka, Masatoshi,Marquez, Victor E.
, p. 1619 - 1625 (2007/10/03)
A series of 6-substituted amino analogs of 9-(2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl) purines (F-ddN) has been synthesized and characterized with the objective of finding compounds which might be superior to existing drugs for the treatment of HIV
Potential Anti-AIDS Drugs. Lipophilic, Adenosine Deaminase-Activated Prodrugs
Barchi, Joseph J.,Marquez, Victor E.,Driscoll, John S.,Ford, Harry,Mitsuya, Hiroaki,et al.
, p. 1647 - 1655 (2007/10/02)
Selected acid-stable (2'-fluoro-2',3'-dideoxyarabinofuranosyl)adenine nucleosides containing methyl groups and other lipophilic functions at various positions in the adenine ring were prepared and evaluated as anti-HIV agents.The N6-methyl (1f)