1327278-20-5

Basic information

• Product Name: 3-(((S)-2-hydroxy-1-phenylethyl-carbamoyl)methyl)-3-methylbutanoic acid
• Synonyms: 3-(((S)-2-hydroxy-1-phenylethyl-carbamoyl)methyl)-3-methylbutanoic acid
• CAS NO: 1327278-20-5
• Molecular Weight: 279.336
• Mol File: 1327278-20-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(((S)-2-hydroxy-1-phenylethyl-carbamoyl)methyl)-3-methylbutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(((S)-2-hydroxy-1-phenylethyl-carbamoyl)methyl)-3-methylbutanoic acid(1327278-20-5)
• EPA Substance Registry System: 3-(((S)-2-hydroxy-1-phenylethyl-carbamoyl)methyl)-3-methylbutanoic acid(1327278-20-5)

Safety Data

• Hazardous Substances Data: 1327278-20-5(Hazardous Substances Data)

Upstream product

• 4160-82-1 3,3-dimethylglutaric anhydride 
• 20989-17-7 (2S)-2-phenylglycinol 

Downstream Products

• 1327277-98-4 (S)-methyl 5-((2-hydroxy-1-phenylethyl)amino)-3,3-dimethyl-5-oxopentanoate 
• 1327278-03-4 methyl 3-(((S)-4,5-dihydro-4-phenyloxazol-2-yl)methyl)-3-methylbutanoate 
• 1327278-10-3 methyl 3-((S)-5,6-dihydro-2-oxo-5-phenyl-2H-1,4-oxazin-3-yl)-3-methylbutanoate 
• 1327278-15-8 methyl 3-methyl-3-((3R,5S)-2-oxo-5-phenylmorpholin-3-yl)butanoate 

Relevant articles and documents

Preparation of α-amino acids by oxidative oxazoline-oxazinone rearrangement-hydrogenation (OOOH). Scope and limitations

The range and scope of the oxidative oxazoline-oxazinone rearrangement-hydrogenation sequence (OOOH)-a short, direct asymmetric synthesis of α-amino acids from carboxylic acids-was explored. The highest yet reported diastereoselectivity for hydrogenation of the oxazinone C=N bond (d.r.=>80:1) is disclosed and rationalized with the aid of ab initio molecular calculations.