132734-41-9

Upstream product

• 91569-18-5 methyl 2-amino-1-naphthoate 
• 59604-96-5 2-hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid methyl ester 
• 947-65-9 methyl 2-hydroxy-1-naphthoate 
• 846540-87-2 2-trifluoromethanesulfonyloxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid methyl ester 
• 900492-90-2 2-(benzhydrylidene-amino)-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid methyl ester 
• 681246-48-0 2-[(tert-butoxycarbonyl)amino]-1-naphthoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 1392091-32-5 N-(1-cyano-5,6,7,8-tetrahydronaphthalen-2-yl)benzenesulfonamide 
• 1392091-22-3 N-[1-(1H-tetrazol-5-yl)-5,6,7,8-tetrahydronaphthalen-2-yl]-benzenesulfonamide 
• 1392091-34-7 2-benzenesulfonylamino-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid amide 
• 681247-05-2 methyl 2-({[2-(methoxycarbonyl)phenyl]sulfonyl}amino)-5,6,7,8-tetrahydro-1-naphthalenecarboxylate 
• 681247-34-7 methyl 2-{[(2-nitrophenyl)sulfonyl]amino}-5,6,7,8-tetrahydro-1-naphthalenecarboxylate 
• 900492-91-3 2-benzenesulfonylamino-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid methyl ester 
• 900492-92-4 2-(4-fluoro-benzenesulfonylamino)-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

A process for the preparation of the compound naphthylamine of process (by machine translation)

The present invention provides a process for preparing compound naphthylamine process method, characterized in that the polarity of the naphthylamine compound dissolved in a solvent proton gender, added with an auxiliary agent, said assistant agent amount is the quality of the states naphthalene amine compound 0.05 - 0.25 times, in order to Ni as the catalyst, hydrogenation reaction at room temperature, after the reaction, filtration, concentration to obtain a tetrahydronaphthalene compounds, the naphthylamine compound of the formula I as shown in the structural formula: the tetrahydronaphthalene amine structural formula of the compound is shown as formula (II) is shown. The reaction of this invention is completed at room temperature, greatly reduced the production energy consumption. At the same time, the reaction almost in the neutral condition, system conditions apply to acid, alkali, heat sensitive all substrate, wide range of application. In addition, because the reaction of the hydrogen pressure is atmospheric, the need to use a high-pressure autoclave equipment, thereby reducing the safety factor in the production process, and reduces equipment investment, greatly reduce the production cost, and is suitable for large-scale industrial production. (by machine translation)

TETRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME

Described herein are tetrazole compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various tetrazole compounds are provided. The compounds are contemplated to have activity against meth

Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties

We have screened molecules for inhibition of MetAP2 as a novel approach toward antiangiogenesis and anticancer therapy using affinity selection/mass spectrometry (ASMS) employing MetAP2 loaded with Mn2+ as the active site metal. After a series

Sulfonamides having antiangiogenic and anticancer activity

Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.

Sulfonamides having antiangiogenic and anticancer activity

Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.