900492-92-4Relevant articles and documents
Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties
Kawai, Megumi,BaMaung, Nwe Y.,Fidanze, Steve D.,Erickson, Scott A.,Tedrow, Jason S.,Sanders, William J.,Vasudevan, Anil,Park, Chang,Hutchins, Charles,Comess, Kenneth M.,Kalvin, Douglas,Wang, Jieyi,Zhang, Qian,Lou, Pingping,Tucker-Garcia, Lora,Bouska, Jennifer,Bell, Randy L.,Lesniewski, Richard,Henkin, Jack,Sheppard, George S.
, p. 3574 - 3577 (2007/10/03)
We have screened molecules for inhibition of MetAP2 as a novel approach toward antiangiogenesis and anticancer therapy using affinity selection/mass spectrometry (ASMS) employing MetAP2 loaded with Mn2+ as the active site metal. After a series
