132741-32-3

Usage

InChI:InChI=1/C8H5F2NO/c9-6-1-5(8(12)4-11)2-7(10)3-6/h1-3,8,12H

Upstream product

• 32085-88-4 3,5-difluorobenzaldehyde 
• 143-33-9 sodium cyanide 
• 773837-37-9 sodium cyanide 

Downstream Products

• 1584127-72-9 C₉H₈F₂O₃ 
• 1584127-69-4 (S)-(+)-methyl 2-acetoxy-2-(3,5-difluorophenyl)acetate 
• 208259-37-4 methyl 2-(3,5-difluorophenyl)-2-hydroxyacetate 
• 1584127-59-2 methyl 2-acetoxy-2-(3,5-difluorophenyl)acetate 

Relevant academic research and scientific papers

Kinetic resolution of mandelate esters via stereoselective acylation catalyzed by lipase PS-30

By using lipase PS-30 as catalyst, the kinetic resolution of a series of racemic mandelate esters has been achieved via stereoselective acylation. The value of kinetic enantiomeric ratio (E) reached up to 197.5. Substituent effect is briefly discussed.

A multigram chemical synthesis of the γ-secretase inhibitor LY411575 and its diastereoisomers

An improved chemical synthesis of N-2((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-l-alaninamide (LY411,575, 9a), a known γ-secretase inhibitor, is described. The key synthetic steps, which

4-ethyl-3-(substituted phenyl)-1-(3-trifluoromethylphenyl)-2-pyrrolidinone derivatives, herbicidal compositions containing them and use thereof

4-Ethyl-3-(phenyl)-1-(3-trifluoromethylphenyl)-2-pyrrolidinones and corresponding compounds bearing a p-substituent on the 1-position phenyl group and/or a substituent on the 3-position phenyl group exhibit selective herbicidal activities against various