132746-47-5Relevant academic research and scientific papers
New stereospecific syntheses and x-ray diffraction structures of (-)-D-erythro- And (+)-L-threo-4-fluoroglutamic acid
Hudlicky, Milos,Merola, Joseph S.
, p. 7403 - 7406 (1990)
Stereospecific syntheses of (+)-L-threo and (-)-D-erythro-4-fluoroglutamic acid are based on the hydrolysis of methyl 1-acetyl-4-fluoro-L-pyrrolidin-5-one-2-carboxylate, prepared from trans- and cis-4-hydroxyprolines, respectively.
Chemistry of 4-fluoroglutamic acid. Part 3. Preparation of the diastereomers of 4-fluoroglutamine and 4-fluoroisoglutamine. An enzymatic access to the antipodes of 4-amino-2-fluorobutyric acid
Tolman, Vladimír,Sedmera, Petr
, p. 5 - 10 (2000)
The pure diastereomers of 4-fluoroglutamine and 4-fluoroisoglutamine were prepared from the corresponding 4-fluoroglutamic acids. Glutamic decarboxylase treatment of the acids led to chiral 2-fluoroGABA.
