132784-29-3Relevant academic research and scientific papers
AMINOTHIENOPYRIDAZINE INHIBITORS OF TAU ASSEMBLY
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Page/Page column 42, (2011/04/24)
The present invention is directed to methods of inhibiting a tauopathy in a patient by administration of a compound of formula (I): Novel aminothienopyridazine compounds are also described.
SYNTHESIS OF NEW POLYFUNCTIONALLY SUBSTITUTED PYRIDAZINES, PHTHALAZINES, CINNOLINES AND THIENOPYRIDAZINES
El-Kousy, Salah,El-Sakka, Ibraheim,El-Torgoman, Abdel Monem,Roshdy, Hesham,Elnagdi, Mohamed Hilmy
, p. 2977 - 2986 (2007/10/02)
The reaction of ethyl 2-arylhydrazono-3-oxobutyrates (Ia, Ib) with active methylene ketones afforded pyridazin-5-carbonitrile derivatives.The methyl function in the ethyl pyridazin-3-carboxylate derivatives IIa, IIb reacted with arylidenemalononitrile to
