132841-86-2Relevant academic research and scientific papers
Synthesis of amphiphilic, chalcogen-based redox modulators with in vitro cytotoxic activity against cancer cells, macrophages and microbes
Du, Peng,Viswanathan, Uma M.,Khairan, Khairan,Buric, Tomislav,Saidu, Nathaniel E. B.,Xu, Zhanjie,Hanf, Benjamin,Bazukyan, Inga,Trchounian, Armen,Hannemann, Frank,Bernhardt, Ingolf,Burkholz, Torsten,Diesel, Britta,Kiemer, Alexandra K.,Schaefer, Karl-Herbert,Montenarh, Mathias,Kirsch, Gilbert,Jacob, Claus
supporting information, p. 25 - 31 (2014/01/06)
Several amphiphilic, chalcogen-based redox modulators have been synthesized which exhibit a widespread, yet in some instances also selective, biological activity which is most likely based on their ability to modulate the intracellular redox balance and t
Intramolecular SH2 macrocyclisations
Baldwin, Jack E.,Adlington, Robert M.,Mitchell, Mark B.,Robertson, Jeremy
, p. 5901 - 5918 (2007/10/02)
The synthesis of 10-15 membered α-methylene macrocyclic lactones from the functionalised allylstannanes (7e)-(7j) is described. Attempts to synthesise analogous 6-9 membered lactones proved unsuccessful, resulting instead in the production of dilactones and AIBN derived adducts.
Radical Reactions in Synthesis: Intramolecular SH2' Macrocyclisations
Baldwin, Jack E.,Adlington, Robert M.,Mitchell, Mark B.,Robertson, Jeremy
, p. 1574 - 1575 (2007/10/02)
The synthesis of 10-15 membered α-methylene lactones 1 from the functionalised allyl stannanes 2 occurs cleanly in moderate to high yield under free radical conditions via an intramolecular SH2' reaction.
