132842-97-8

Basic information

• Product Name: 8-acetyl-1-methyloctahydro-4(1H)-azulenone
• Synonyms: 8-acetyl-1-methyloctahydro-4(1H)-azulenone
• CAS NO: 132842-97-8
• Molecular Formula: C13H20O2
• Molecular Weight: 208.2967
• Mol File: 132842-97-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-acetyl-1-methyloctahydro-4(1H)-azulenone(CAS DataBase Reference)
• NIST Chemistry Reference: 8-acetyl-1-methyloctahydro-4(1H)-azulenone(132842-97-8)
• EPA Substance Registry System: 8-acetyl-1-methyloctahydro-4(1H)-azulenone(132842-97-8)

Safety Data

• Hazardous Substances Data: 132842-97-8(Hazardous Substances Data)

Upstream product

• 132842-92-3 (-)-isoapoaromadendrone 

Relevant articles and documents

The conversion of natural (+)-aromadendrene into chiral synthons-I

(-)-Apoaromadendrone (3) can be obtained easily in large quantities from (+)-aromadendrene which is the main constituent in a commercially available distillation tail of the oil of Eucalyptus globules. Acid catalyzed selective cleavage of the C3-C4 bond of the cyclopropane ring in 3 gave (-)-isoapoaromadendrone(9) in high yield. The regioselectivity of the cyclopropane ring opening was proved by NMR spectroscopy in combination with chemical transformations. Ozonolysis of 9 afforded the keto alcohol 14 which is a suitable chiral intermediate for the syntheses of guaianes and guaianolides.