132871-09-1 Usage
Piperazine derivative
A chemical compound derived from the base structure of piperazine, which is a heterocyclic organic compound structured as a six-membered ring with two nitrogen atoms.
Benzyl group
A phenyl group attached to a methylene group (-CH2-), which is connected to the piperazine ring in 1-BENZYL-3-METHYL-PIPERAZINE-2,5-DIONE, contributing to its chemical structure and properties.
Methyl group
A -CH3 functional group attached to the piperazine ring in the compound, which also influences its chemical structure and properties.
Carbonyl group
An oxygen double-bonded to a carbon atom (C=O), which is present at the 2 and 5 positions of the piperazine ring, giving the compound its diketopiperazine structure.
Diketopiperazine structure
A type of cyclic peptide structure formed by the condensation of two amino acids, resulting in a six-membered ring. 1-BENZYL-3-METHYL-PIPERAZINE-2,5-DIONE has this structure due to the presence of the carbonyl groups at positions 2 and 5 of the piperazine ring.
Pharmaceutical research and development
1-BENZYL-3-METHYL-PIPERAZINE-2,5-DIONE has potential applications in the pharmaceutical industry as a precursor in the synthesis of various bioactive compounds and pharmaceutical agents.
Biological activities
1-BENZYL-3-METHYL-PIPERAZINE-2,5-DIONE may exhibit biological activities, which could be studied further to understand its pharmacological properties and potential therapeutic applications.
Medicinal chemistry
The compound is a valuable tool for medicinal chemists and researchers due to its potential applications in drug development and its unique chemical structure.
Further research needed
Additional studies are required to fully understand the potential uses and properties of 1-BENZYL-3-METHYL-PIPERAZINE-2,5-DIONE, including its pharmacological effects, safety, and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 132871-09-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,8,7 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 132871-09:
(8*1)+(7*3)+(6*2)+(5*8)+(4*7)+(3*1)+(2*0)+(1*9)=121
121 % 10 = 1
So 132871-09-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O2/c1-9-12(16)14(8-11(15)13-9)7-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,13,15)/t9-/m1/s1
132871-09-1Relevant articles and documents
Highly efficient enantioselective synthesis of 1,3-disubstituted 2,5-diketopiperazine derivatives via microwave irradiation
Han, Si Yeon,Gong, Young-Dae
supporting information, p. 3426 - 3434 (2019/11/03)
Chiral 2,5-diketopiperazine (2,5-DKP) derivatives have a broad range of biological activities in the medicinal field. The synthetic protocols of 1,3-disubstituted 2,5-DKPs via base-catalyzed cyclization of chloroacetamide have been reported. However, there are several drawbacks, such as an overly long reaction time, low to moderate yield, and racemization of the products. The sequence modified herein of 1,3-disubstituted 2,5-DKPs involves microwave-assisted cyclization. It increases yields and reduces reaction time. Furthermore, employing N-PMB protection prevents racemization, which frequently occurs in the base-catalyzed cyclization reaction. Consequently, the rapid synthetic method of enantiomerically pure 1,3-disubstituted 2,5-DKPs via microwave reaction was established successfully.
